
Patheon by Thermo Fisher Scientific
https://patheon.com
4766 LaGuardia Drive
St. Louis, MO, 63134-3117
USA
St. Louis, MO, 63134-3117
USA
Categories
About Patheon by Thermo Fisher Scientific:
Thermo Fisher Scientific provides pharma services solutions for drug development, clinical trial logistics, and commercial manufacturing to customers through its Patheon brand. With more than 65 locations around the world, they provide integrated, end-to-end capabilities across all phases of development, including API, biologics, viral vectors, cGMP plasmids, formulation, clinical trials solutions, logistics services, and commercial manufacturing and packaging.
Service Offerings:
- Biologics (Large Molecule) Commercial Manufacturing
- Formulation & Development
- Process development for all mammalian cell lines
- In-house analytical expertise
- QC and QA
- Expertise in fed-batch and perfusion processes
- In-house and partnered cell line development – CHO (Chinese Hamster Ovary)
- Single-use and flexible stainless steel technologies
- Upstream and downstream process development expertise
- Analytical Laboratory Capabilities
- Peptide mapping
- Sequence confirmation and PTM/degradation by LC-MS/MS
- Potency (binding ELISA. enzymatic activity assays. cell-based potency assay)
- Aggregates by SEC-MALS Impurity ( residual Protein A. HCP. residual DNA)
- Subvisible particles by LO
- Quantity: protein A/G HPLC
- ELISA titer assay
- A280
- Amino Acid Analysis by UPLC
- Capillary electrophoresis (CE-SDS. cIEF. CE-LIF)
- Extinction Coefficient determination
- DOE for method development and method validation
- N-Glycan profiling by fluorescence-labeling and normal phase HPLC or CE
- Protein conformation characterization using capillary DSC
- Sialic acid content and NANA/NAGA ratio measurement
- High throughput CE-SDS & glycan profiling with microfluidic instrument
- Monosaccharide Analysis
- Charged Aerosol Detector (CAD) used to test Polysorbate
- Anti-foam
- Pluronic
Reviews:
No Reviews